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Citalopram was first synthesized in 1972 by scientists at the pharmaceutical company Lundbeck and was first marketed in 1989 in Denmark. It was first marketed in the US in 1998.[1] The patent expired in 2003, allowing other companies to legally produce generic versions. Lundbeck has released escitalopram and acquired a new patent for it. In the United States, Forest Labs manufactures and markets the drug.

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Brand names

Citalopram is sold under these brand-names:

  • Akarin (Denmark, Nycomed)
  • C Pram S (India)
  • Celapram (Australia,[2] New Zealand),
  • Celexa (U.S. and Canada, Forest Laboratories, Inc.)
  • Celica (Australia)[2]
  • Ciazil (Australia,[2] New Zealand)
  • Cilate (South Africa)
  • Cilift (South Africa)
  • Cimal (South America, by Roemmers and Recalcine)
  • Cipralex (South Africa)
  • Cipram (Turkey, Denmark, H. Lundbeck A/S)
  • Cipramil (Australia,[2] Brazil, Belgium, Finland, Germany, Netherlands, Iceland, Ireland, Israel, Norway, Sweden, United Kingdom, New Zealand, South Africa, Russia)
  • Cipraned, Cinapen (Greece)
  • Ciprapine (Ireland)
  • Ciprotan (Ireland)
  • Citabax, Citaxin (Poland)
  • Citalec (Slovakia, Czech Republic)
  • Citalex (Iran, Serbia)
  • Citalo (Australia,[2] Egypt)
  • Citalopram (USA, United Kingdom, New Zealand, Denmark, Finland, Germany, Spain, Sweden, Switzerland, Canada)
  • Citol (Russia)
  • Citox (Mexico)
  • Citrol (Europe and Australia)[2]
  • Citta (Brazil)
  • Dalsan (Eastern Europe)
  • Denyl (Brazil)
  • Elopram (Italy)
  • Estar (Pakistan)
  • Humorup (Argentina)
  • Humorap (Peru, Bolivia)
  • Oropram (Iceland, Actavis),
  • Opra (Russia)
  • Pram (Russia)
  • Pramcit (Pakistan)
  • Procimax (Brazil)
  • Recital (Israel, Thrima Inc. for Unipharm Ltd.)
  • Sepram (Finland)
  • Seropram (various European countries, including Czech Republic)
  • Szetalo (India)
  • Talam (Europe and Australia)[2]
  • Temperax (Chile, Peru, Argentina)
  • Vodelax (Turkey)
  • Zentius (South America, by Roemmers and Recalcine)
  • Zetalo (India)
  • Zylotex (Portugal)[3]

Medical uses

Citalopram HBr tablets in 20-mg (coral, marked 508) and 40-mg (white, marked 509), and a United States one-cent coin (size 19.05 mm/0.75 in)


In the National Institute for Health and Clinical Excellence ranking of 10 antidepressants for efficacy and cost-effectiveness[4] citalopram is fifth in effectiveness (after mirtazapine, escitalopram, venlafaxine, and sertraline) and fourth in cost-effectiveness. The ranking results were based on the meta-analysis by Andrea Cipriani.[5] In another analysis by Cipriani, citalopram was found to be more efficacious than paroxetine and reboxetine, and more acceptable than tricyclics, reboxetine, and venlafaxine, but less efficacious than escitalopram.[6]

Evidence for effectiveness of citalopram for treating depression in children is uncertain.[7][8]

Panic disorder

Citalopram is licensed in the UK and other European countries [9][10] for panic disorder, with or without agoraphobia. The dose is 10 mg/d for a week, increasing to 20–30 mg/d, with a maximum of 40 mg/d.[11]


Stop Thinking About It :o


Citalopram is frequently used off-label to treat anxiety, panic disorder, dysthymia[12] premenstrual dysphoric disorder, body dysmorphic disorder and obsessive–compulsive disorder.[13]
  1. Benjamin Rawe and Paul May for Molecule of the Month. 2009 Citalopram: A new treatment for depression Page accessed 16 February 2015
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 "Pharmaceutical Benefits Scheme (PBS) - Citalopram". Australian Government. 
  3. "Citalopram". International. 
  4. See p410 of "National Clinical Practice Guideline 90. Depression: The treatment and management of depression in adults, updated edition (2010).". National Institute for Health and Clinical Excellence (UK). 
  5. Cipriani, A.; Furukawa, T. A.; Salanti, G.; Geddes, J. R.; Higgins, J. P.; Churchill, R.; Watanabe, N.; Nakagawa, A.; Omori, I. M.; McGuire, H.; Tansella, M.; Barbui, C. (2009). "Comparative efficacy and acceptability of 12 new-generation antidepressants: A multiple-treatments meta-analysis". The Lancet. 373 (9665): 746–58. PMID 19185342. doi:10.1016/S0140-6736(09)60046-5. 
  6. Cipriani, A.; Purgato, M.; Furukawa, T. A.; Trespidi, C.; Imperadore, G.; Signoretti, A.; Churchill, R.; Watanabe, N.; Barbui, C. (2012). Cipriani, Andrea, ed. "Citalopram versus other anti-depressive agents for depression". The Cochrane Library. 7 (7): CD006534. PMC 4204633free to read. PMID 22786497. doi:10.1002/14651858.CD006534.pub2. 
  7. Cohen, D (2007). "Should the use of selective serotonin reuptake inhibitors in child and adolescent depression be banned?". Psychotherapy and psychosomatics. 76 (1): 5–14. PMID 17170559. doi:10.1159/000096360. 
  8. Carandang C, Jabbal R, Macbride A, Elbe D (November 2011). "A review of escitalopram and citalopram in child and adolescent depression". J Can Acad Child Adolesc Psychiatry. 20 (4): 315–24. PMC 3222577free to read. PMID 22114615. 
  9. Urząd Rejestracji Produktów Leczniczych, Wyrobów Medycznych i Produktów Biobójczych (Office for Registration of Medicinal Products, Medical Devices and Biocides) "Archived copy" (PDF). Archived from the original (PDF) on 5 November 2013. Retrieved 24 September 2013. 
  10. British National Folmulary
  11. Perna G, Bertani A, Caldirola D, Smeraldi E, Bellodi L. A comparison of citalopram and paroxetine in the treatment of panic disorder: a randomized, single-blind study" Pharmacopsychiatry 2001; 34: 85–90
  12. Hellerstein, DJ; Batchelder, S; Miozzo, R; Kreditor, D; Hyler, S; Gangure, D; Clark, J (2004). "Citalopram in the treatment of dysthymic disorder". Int Clin Psychopharmacol. 19 (3): 143–8. PMID 15107656. doi:10.1097/00004850-200405000-00004. 
  13. Poore J. "Celexa (citalopram hydrobromide)". Crazy Meds.