Imipramine

Imipramine is used in the treatment of depression, such as depression associated with agitation or anxiety. It is similar in efficacy to the antidepressant drug moclobemide.

It has also been used to treat nocturnal enuresis because of its ability to shorten the time of delta wave stage sleep, where wetting occurs.

Reading scholarly articles about Imipramine, all I manage to take from them are endless cvharts which repeat the words HUMAN / RODENT / RAT in their effects and so I don't feel any wiser, or indeed better.